Friday, February 23, 2007

Zyprexa Does Not Cause Diabetes?

That's not what one set of physicians believe, despite Lilly's protestations to the contrary. Here's what they recently reported regarding one case:
The authors report a case with life-threatening hyperglycemia and acidosis in a patient with no previous diabetic history following treatment with olanzapine. A 35-year-old woman with a history of bipolar affective disorder treated with olanzapine presented with severe diabetic ketoacidosis. She had no prior history of diabetes or risk factors for diabetes. Glycosylated hemoglobin (HbA1c) on admission blood sample suggested that long-term glycemic control had been poor. The authors postulate that treatment with olanzapine precipitated hyperglycemia, an elevated creatine kinase level, and a high amylase level.
Perhaps someone should have told these physicians that Zyprexa is a safe, gentle psychotropic that could not possibly induce such nasty side effects.

2 comments:

Anonymous said...

Not only diabetes, but apparently on her way to kidney failure as well with a high creatine level. A woman in Alaska won a few million for lithium taken as prescribed causing kidney failure, too bad this woman probably isn't reading your blog.

Marissa Miller said...

CL - just a warning that some of my comments aren't getting through. I don't know if others are having this problem. (Good thing I wrote some of them down on the train...)

On this I wrote:

"Perhaps someone should have told these physicians that Zyprexa is a safe, gentle psychotropic that could not possibly induce such nasty side effects."

LOL.

That was important, huh? ;)